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SARS-CoV-2 and cholesterol
The Nebion compendium has been enriched with deeply curated in-vivo and in-vitro COVID-19/SARS-CoV-2 studies.
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Curated COVID-19 data
NEBION continuously curates COVID-19 related gene expression studies and integrates them into GENEVESTIGATOR®.
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Genes & Covid-19 severity
A recent genome-wide association study (Ellinghaus et al., 2020) has identified genetic variations in two loci associated with severe Covid-19 outcome.
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Response to SARS-CoV-2
Explore transcriptional response of host cells to infection with the novel SARS-Cov-2 virus in GENEVESTIGATOR®!
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Priming protease Furin
SARS-Cov-2 differs from closely related coronaviruses (including SARS-Cov) in the sequence of its spike protein, among other differences.
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Regulation of LY6E
Recently, Pfaender et al. (2020) reported that the lymphocyte antigen 6 complex, locus E (LY6E) protein potently restricts cellular infection by multiple coronaviruses, including SARS-CoV-2.