At the heart of NEBION's curated data and
products is scientific rigor and many years of research experience.
Over 80% of NEBION employees have a PhD in either molecular biology,
informatics, statistics, physics or electrical engineering. We strive
to develop products and services at the highest level of quality and
scientific stringency. Besides applying our scientific skills and
curiosity into developing innovative products and services, NEBION
participates in various international research projects and publishes
novel methods for bioinformatic data analysis and curation.
Mermod M, Hiou-Feige A, Bovay E, Roh V, Sponarova J,
Bongiovanni M, Vermeer DW, Lee JH, Petrova TV, Rivals JP, Monnier Y,
Tolstonog GV, Simon C (2018) Mouse model of postsurgical
primary tumor recurrence and regional lymph node metastasis
progression in HPV-related head and neck cancer. Int J Cancer. 2018
Jan 4.
Dostalova A, Rommelaere S, Poidevin M, Lemaitre B (2017) Thioester-containing
proteins regulate the Toll pathway and play a role in Drosophila
defence against microbial pathogens and parasitoid wasps. BMC Biol.
2017 Sep 5;15(1):79.
Macuchova E, Nohejlova K, Sevcikova M, Hrebickova I, Slamberova
R (2017) Sex differences in the strategies of spatial
learning in prenatally-exposed rats treated with various drugs in
adulthood. Behavioural Brain Research; 327:83-93. ]
Jiraskova A, Bortolussi G, Dostalova G, EremiaSova L, Golan L,
Danzig V, Linhart A, Vitek L. (2017) Serum Bilirubin Levels
and Promoter Variations in HMOX1 and UGT1A1 Genes in Patients with
Fabry Disease. Oxid Med Cell Longev 2017:9478946.
Andersson A, Bluwstein A, Kumar N, Teloni F, Traenkle J, Baudis
M, Altmeyer M, Hottiger MO (2016) PKCα and HMGB1
antagonistically control hydrogen peroxide-induced poly- ADP-ribose
formation. Nucleic Acids Research, 19;44 (16): 7630-45.
Macuchova E, Sevcikova M, Hrebickova I, Nohejlova K, Slamberova
R (2016) How various drugs affect anxiety-related behavior in
male and female rats prenatally exposed to methamphetamine.
International Journal of Developmental Neuroscience; 51:1-11.
Hajkova A, Techlovska S, Dvorakova M, Chambers JN, KumpoSt J,
Hubalkova P, Prezeau L, Blahos J. (2016) SGIP1 alters
internalization and modulates signaling of activated cannabinoid
receptor 1 in a biased manner. Neuropharmacology. 2016
Aug;107:201-214. doi: 10.1016.
Mrizova I, Moserova M, Milichovsky J, Sulc M, Kizek R,
Kubackova K, Arlt VM, Stiborova M. (2016) Heterologous
expression of human cytochrome P450 2S1 in Escherichia coli and
investigation of its role in metabolism of benzo[a]pyrene and
ellipticine. Monatsh Chem 147:881-888.
Valny M, Honsa P, Kirdajova D, Kamenik Z, Anderova M. (2016) Tamoxifen
in the mouse brain: Implications for fate-mapping studies using the
tamoxifen-inducible Cre-loxP system. Frontiers in Cellular
Neuroscience 10, 243, DOI: 10.3389/fncel.2016.00243.
Honsa P, Valny M, Kriska J, Matuskova H, Harantova L, Kirdajova
D, Valihrach L, Androvic P, Kubista M, Anderova M. (2016) Generation
of reactive astrocytes from NG2 cells is regulated by sonic hedgehog.
Glia 64 (9), 1518-1531.
Kalferstova L, Vilimovska Dedeckova K, Antuskova M, Melter O,
Drevinek P. J (2016) How and why to monitor Pseudomonas
aeruginosa infections in the long term at a cystic fibrosis centre. Hosp
Infect. 2016 Jan;92(1):54-60.
Polakova E, Illaste A, Niggli E, Sobie EA. (2015) Maximal
acceleration of Ca2+ release refractoriness by β-adrenergic
stimulation requires dual activation of kinases PKA and CaMKII in
mouse ventricular myocytes. J Physiol. 593(6):1495-507.
Andersson A, Minotti R, Hottiger MO (2015) ARTD1
Suppresses Interleukin 6 Expression by Repressing MLL1- Dependent
Histone H3 Trimethylation. Molecular and Cellular Biology, 35 (18):
3189-99
Arlt VM, Krais AM, Godschalk RW, Riffo-Vasquez Y, Mrizova I,
Roufosse CA, Corbin C, Shi Q, Frei E, Stiborova M, van Schooten FJ,
Phillips DH and Spina D. (2015) Pulmonary inflammation
impacts on CYP1A1-mediated respiratory tract DNA damage induced by
the carcinogenic air pollutant benzo[a]pyrene. Toxicol Sci
146(2):213-25.
Lenicek M, Duricova D, Hradsky O, Dusatkova P, Jiraskova A,
Lukas M, Nachtigal P, Vitek L. (2014) The relationship
between serum bilirubin and Crohn's disease. Inflamm Bowel Dis
20(3):481-7.
Techlovska S, Chambers JN, Dvorakova M, Petralia RS, Wang YX,
Hajkova A, Nova A, Frankova D, Prezeau L, Blahos J (2014) Metabotropic
glutamate receptor 1 splice variants mGluR1a and mGluR1b combine in
mGluR1a/b dimers in vivo. Neuropharmacology. 2014 Nov;86:329-336.
doi: 10.1016.
Honsa P, Pivonkova H, Harantova L, Butenko O, Kriska J, Dzamba
D, Rusnakova V, Valihrach L, Kubista M, Anderova M (2014) Increased
expression of hyperpolarization-activated cyclic nucleotide-gated
(HCN) channels in reactive astrocytes following ischemia. Glia. 2014
Jul 14. DOI: 10.1002/glia.22721.
Stiborova M, Cerna V, Moserova M, Mrizova I, Arlt VM and E Frei
(2014) The anticancer drug ellipticine activated with
cytochrome P450 mediates DNA damage determining its pharmacological
efficiencies: studies with rats, Hepatic Cytochrome P450 Reductase
Null (HRN) mice and pure enzymes. Int J Mol Sci 16(1): 284-306.
Macuchova E, Nohejlova K, Slamberova R (2014) Gender
differences in the effect of adult amphetamine on cognitive functions
of rats prenatally exposed to methamphetamine. Behavioural Brain
Research; 270: 8-17.
Vitek L, Gbelcova H, Muchova L, Vanova K, Zelenka J, Konickova
R, Suk J, Zadinova M, Knejzlik Z, Ahmad S, Fujisawa T, Ahmed A, Ruml
T. (2014) Antiproliferative effects of carbon monoxide on
pancreatic cancer. Dig Liver Dis 46(4):369-75.
Cuperus FJ, Schreuder AB, van Imhoff DE, Vitek L, Vanikova J,
Konickova R, Ahlfors CE, Hulzebos CV, Verkade HJ (2013) Beyond
plasma bilirubin: the effects of phototherapy and albumin on brain
bilirubin levels in Gunn rats. J Hepatol 58(1):134-40.
Kyrychenko S, Polakova E, Kang C, Pocsai K, Ullrich ND, Niggli
E, Shirokova N. (2013) Hierarchical accumulation of RyR
post-translational modifications drives disease progression in
dystrophic cardiomyopathy. Cardiovasc Res. 97(4):666-75.
Sponarova J, Nuvolone M, Whicher C, Frei N, Kana V, Schwarz P,
Westermark GT, Aguzzi A (2013) Efficient amyloid A clearance
in the absence of immunoglobulins and complement factors. Am J
Pathol. 2013 Apr;182(4):1297-307.
Dostalova A, Kaeser S, Cristodero M, Schimanski B (2013) The
nuclear mRNA export receptor Mex67-Mtr2 of Trypanosoma brucei
contains a unique and essential zinc finger motif. Mol Microbiol.
2013 May;88(4):728-39
Dedeckova K, Kalferstova L, Strnad H, Vavrova J and Drevinek P
(2013) Novel diagnostic PCR assay for Burkholderia
cenocepacia epidemic strain ST32 and its utility in monitoring
infection in cystic fibrosis patients. Cyst Fibros. 2013 Jan 11.
Dedeckova K, Fila L, Skalicka V, Bartosova J, Kucerova T,
Vavrova V, Zemkova D, Kalferstova L, Melter O, Cinek O, Drevinek P.
(2012) PCR detection of Burkholderia cepacia complex as one
of key factors to handle a longterm outbreak. J Cyst Fibros. 2012
Sep;11(5):440-5.
Jiraskova A, Novotny J, Novotny L, Vodicka P, Pardini B,
Naccarati A, Schwertner HA, Hubacek JA, Puncocharova L, Smerhovsky Z,
Vitek L. (2012) Association of serum bilirubin and promoter
variations in HMOX1 and UGT1A1 genes with sporadic colorectal cancer.
Int J Cancer 131(7):1549-55.
O'Connor T, Frei N, Sponarova J, Schwarz P, Heikenwalder M,
Aguzzi A (2012) Lymphotoxin, but not TNF, is required for
prion invasion of lymph nodes. PLoS Pathog. 2012;8(8):e10028675.
Dostalova A, Votypka J, Favreau AJ, Barbian KD, Volf P,
Valenzuela JG, Jochim RC (2011) The midgut transcriptome of
Phlebotomus (Larroussius) perniciosus, a vector of Leishmania
infantum: comparison of sugar fed and blood fed sand flies. BMC
Genomics. 2011 May 10;12:223
Ballmer-Hofer K, Andersson AE, Ratcliffe LE, Berger P (2011) Neuropilin-1
promotes VEGFR-2 trafficking through Rab11 vesicles thereby
specifying signal output. Blood, 118 (3): 816-826
Polakova E, Zahradnikova A Jr, Pavelkova J, Zahradnik I,
Zahradnikova A. (2008) Local calcium release activation by
DHPR calcium channel openings in rat cardiac myocytes. . J Physiol
586(16):3839-54.
Scrima A, Konickova R, Czyzewski BK, Kawasaki Y, Jeffrey PD,
Groisman R, Nakatani Y, Iwai S, Pavletich NP, Thomä NH (2008) Structural
basis of UV DNA-damage recognition by the DDB1-DDB2 complex. Cell
135(7):1213-23.
Sponarova J, Mustard KJ, Horakova O, Flachs P, Rossmeisl M,
Brauner P, Bardova K, Thomason-Hughes M, Braunerova R, Janovska P,
Hardie DG, Kopecky J (2005) Involvement of AMP-activated
protein kinase in fat depot-specific metabolic changes during
starvation. FEBS Lett. 2005 Nov 7;579(27):6105-10
Kucharewicz W, Distelfeld A, Bilger W, Mueller M, Munne-Bosch
S, Hensel G, Krupinska K. (2017) Acceleration of leaf
senescence is slowed down in transgenic barley plants deficient in
the DNA/RNA-binding protein WHIRLY1. J Exp Bot. 68(5):983-996.
Kim C, Meskauskiene R, Zhang S, Lee KP, Lakshmanan Ashok M,
Blajecka K, Herrfurth C, Feussner I, Apel K (2012) Chloroplasts
of Arabidopsis are the source and a primary target of a
plant-specific programmed cell death signaling pathway. Plant Cell.
2012 Jul;24(7):3026-39
Meskauskiene R, Wuersch M, Laloi C, Vidi PA, Coll NS, Kessler
F, Baruah A, Kim C, Apel K (2009) A mutation in the
Arabidopsis mTERF-related plastid protein SOLDAT10 activates
retrograde signaling and suppresses (1)O(2)-induced cell death.
Plant J. 2009 Nov;60(3):399-410
Baerenfaller K, Grossmann J, Grobei MA, Hull R, Hirsch-Hoffmann
M, Yalovsky S, Zimmermann P, Grossniklaus U and W Gruissem (2008) Genome-scale
proteomics reveals Arabidopsis thaliana gene models and proteome
dynamics. Science 320 (5878), 938-941
Vanderauwera S, Zimmermann P, Rombauts S, Vandenabeele S,
Langebartels C, Gruissem W, Inze D and F van Breusegem (2005) Genome-wide
analysis of hydrogen peroxide-regulated gene expression in
Arabidopsis reveals a high light-induced transcriptional cluster
involved in anthocyanin biosynthesis. Plant Physiology 139 (2),
806-821 [
Abstract]
Zimmermann P, Regierer B, Kossmann J, Frossard E, Amrhein N and
M Bucher (2004) Differential expression of three purple acid
phosphatases from potato. Plant Biology 6 (05), 519-528 [
Abstract]
Zimmermann P, Zardi G, Lehmann M, Zeder C, Amrhein N, Frossard
E and M Bucher (2003) Engineering the rootâsoil interface via
targeted expression of a synthetic phytase gene in trichoblasts.
Plant Biotechnology Journal 1 (5), 353-360
Meskauskiene R, Nater M, Goslings D, Kessler F, op den Camp R,
Apel K (2001) FLU: a negative regulator of chlorophyll
biosynthesis in Arabidopsis thaliana. Proc Natl Acad Sci U S A. 2001
Oct 23;98(22):12826-31
